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Article

Synaptic defects in a Drosophila model of congenital muscular dystrophy.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 2 Apr 2008

Wairkar Yogesh P, Fradkin Lee G, Noordermeer Jasprina N, DiAntonio Aaron

Abstract excerpt

The congenital muscular dystrophies present in infancy with muscle weakness and are often associated with mental retardation. Many of these inherited disorders share a common etiology: defective O-glycosylation of alpha-dystroglycan, a component of the dystrophin complex. Protein-O-mannosyl transferase 1 (POMT1) is the first enzyme required for the glycosylation of alpha-dystroglycan, and mutations in the POMT1...

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Identifiers

PMID: 18385336
DOI: 10.1523/JNEUROSCI.0478-08.2008
PMCID: PMC6671091

Genes

POMT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Synaptic defects in a Drosophila model of congenital muscular dystrophy.PMID 18385336Read ↗

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