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Article

Transformation by bovine papillomavirus type 1 E6 requires paxillin.

Journal of virology - 1 Jun 2008

Wade Ramon, Brimer Nicole, Vande Pol Scott

Abstract excerpt

Papillomavirus E6 proteins are adapters that change the function of cellular regulatory proteins. The bovine papillomavirus type 1 E6 (BE6) binds to LXXLL peptide sequences termed LD motifs (consensus sequence LDXLLXXL) on the cellular protein paxillin that is a substrate of Src and focal adhesion kinases. Anchorage-independent transformation induced by BE6 required both paxillin and BE6-binding LD motifs on...

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Source

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Identifiers

PMID: 18385245
DOI: 10.1128/JVI.02747-07
PMCID: PMC2395150

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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