Article
Alpha 1 antichymotrypsin genotype is associated with increased risk of prostate carcinoma and PSA levels.
Anticancer research - 1 Jan 2000
Licastro Federico, Bertaccini Alessandro, Porcellini Elisa, Chiappelli Martina, Pernetti Remigio, Sanguedolce Francesco, Marchiori Debora, Martorana Giuseppe
Abstract excerpt
BACKGROUND: Prostate cancer (PCa) is the most common non-skin cancer among men in Western countries. Inflammation appears to be involved in the pathogenesis of PCa. Recent studies have shown that many inflammatory genes are associated with the risk of PCa. Alpha 1 antichymotrypsin (ACT) is an acute phase protein and it is part of the circulating prostate specific antigen (PSA). PATIENTS AND METHODS: Allele and...
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