Article
[The use of noben for correction of mitochondrial disorders in Friedrich's disease].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 1 Jan 2007
Ershova M V, Illarioshkin S N, Sukhorukov V S
Abstract excerpt
The results of treatment with noben (idebenon), an improved structural analogue of coenzyme Q10, of 34 patients with Friedrich's disease are presented. In all cases, the clinical diagnosis was confirmed by the presence of a typical mutation, an expansion of trinucleotide GAA-repeats, in the FRDA gene. All patients received noben as a main drug in dosage 5 mg/kg daily during 3 months. An examination of the...
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