Article
On the structural repertoire of pools of short, random RNA sequences.
Journal of theoretical biology - 21 Jun 2008
Stich Michael, Briones Carlos, Manrubia Susanna C
Abstract excerpt
A detailed knowledge of the mapping between sequence and structure spaces in populations of RNA molecules is essential to better understand their present-day functional properties, to envisage a plausible early evolution of RNA in a prebiotic chemical environment and to improve the design of in vitro evolution experiments, among others. Analysis of natural RNAs, as well as in vitro and computational studies, show...
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