Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Premature thelarche from phenotype to genotype.

Pediatric endocrinology reviews : PER - 1 Mar 2008

Codner Ethel, Román Rossana

Abstract excerpt

Premature thelarche is a benign condition, which has been described as a "variant of puberty". Early breast development is especially prevalent during the first year of life, when the gonadal axis is usually active. Ultrasensitive bioassays have described higher estrogen levels in these girls compared to controls. Some cases of premature thelarche may also exhibit increased growth velocity and/or bone age,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to GNAS gene
Share to Genotype
Share to Puberty, Precocious

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to GTP-Binding Protein alpha Subunits, Gs

Share to Phenotype

Share to Breast

Share to Chromogranins

Source

Identifiers

PMID: 18367996

Genes

GNAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Premature thelarche from phenotype to genotype.PMID 18367996Read ↗

A case of premature thelarche with no central cause or genetic variants within the estrogen receptor signaling pathway.Semantic proximity Read ↗

Premature adrenarche.Semantic proximity Read ↗

No association between estrogen receptor gene polymorphisms and premature thelarche in girls.Semantic proximity Read ↗

Pubertal Progression and Reproductive Hormones in Healthy Girls With Transient Thelarche.Semantic proximity Read ↗

Activating GNAS1 gene mutations in patients with premature thelarche.Semantic proximity Read ↗

Reproductive hormones during pubertal transition in girls with transient Thelarche.Semantic proximity Read ↗

Endocrine and molecular investigations in a cohort of 25 adolescent males with prominent/persistent pubertal gynecomastia.Semantic proximity Read ↗

Premature thelarche and granulosa cell tumors: a search for FSH receptor and G5alpha activating mutations.Semantic proximity Read ↗

Continuum of phenotypes and sympathoadrenal function in premature adrenarche.Semantic proximity Read ↗

Premature adrenarche--normal variant or forerunner of adult disease?Semantic proximity Read ↗

Female phenotype at birth and postnatal masculinization, during the first months of life, associated with transient 5 alpha-reductase 2 deficiency in a preterm infant. A timing defect syndrome?Semantic proximity Read ↗

Candidate gene analysis in premature pubarche and adolescent hyperandrogenism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.