Article
Phenolic lipids synthesized by type III polyketide synthase confer penicillin resistance on Streptomyces griseus.
The Journal of biological chemistry - 16 May 2008
Funabashi Masanori, Funa Nobutaka, Horinouchi Sueharu
Abstract excerpt
Type III polyketide synthases (PKSs) found in plants, fungi, and bacteria synthesize a variety of aromatic polyketides. A Gram-positive, filamentous bacterium Streptomyces griseus contained an srs operon, in which srsA encoded a type III PKS, srsB encoded a methyltransferase, and srsC encoded a f...
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