Article
Requirements for surface expression and function of adhesin P1 from Streptococcus mutans.
Infection and immunity - 1 Jun 2008
Crowley Paula J, Seifert Trevor B, Isoda Ryutaro, van Tilburg Marloes, Oli Monika W, Robinette Rebekah A, McArthur William P, Bleiweis Arnold S, Brady L Jeannine
Abstract excerpt
In this report, we define requirements for the successful translocation and functional maturation of the adhesin P1 of Streptococcus mutans. Conformational epitopes recognized by anti-P1 monoclonal antibodies (MAbs) were further characterized, thus facilitating the use of particular MAbs as tools to monitor the locations of various forms of the protein. We show that correct localization of P1 is dependent on...
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