Article
The characteristics of the cell-mediated immune response identify different profiles of occult hepatitis B virus infection.
Gastroenterology - 1 May 2008
Zerbini Alessandro, Pilli Massimo, Boni Carolina, Fisicaro Paola, Penna Amalia, Di Vincenzo Paola, Giuberti Tiziana, Orlandini Alessandra, Raffa Giuseppina, Pollicino Teresa, Raimondo Giovanni, Ferrari Carlo, Missale Gabriele
Abstract excerpt
BACKGROUND & AIMS: Hepatitis B virus (HBV) DNA detection in serum and/or in the liver of hepatitis B surface antigen (HBsAg)-negative patients with or without serologic markers of previous viral exposure is defined as occult HBV infection. Because the role of the adaptive response in keeping HBV replication under control in occult infection still is undefined, this study was performed to characterize the features...
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