Article
Drosophila myosin V is required for larval development and spermatid individualization.
Developmental biology - 1 Oct 2005
Mermall Valerie, Bonafé Nathalie, Jones Lynn, Sellers James R, Cooley Lynn, Mooseker Mark S
Abstract excerpt
Class V myosins are multifunctional molecular motors implicated in vesicular traffic, RNA transport, and mechanochemical coupling of the actin and microtubule-based cytoskeletons. To assess the function of the single myosin V gene in Drosophila (MyoV), we have characterized both deletion and truncation alleles. Mutant animals exhibit no detectable defects during embryogenesis but are delayed in larval...
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