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Article

Comparison of the rapidly evolving KIR locus in Parsis and natives of India.

Immunogenetics - 1 Apr 2008

Kulkarni S, Single R M, Martin M P, Rajalingam R, Badwe R, Joshi N, Carrington M

Abstract excerpt

The extreme variability at the Killer cell Immunoglobulin-like Receptor (KIR) locus along with that of the genes encoding their ligands, HLA class I, appears to modulate risk for viral, autoimmune, and malignant diseases, and reproductive failure. Differences in KIR gene and haplotype frequencies across world populations may reflect some combination of ancestral genotypes, locale-specific selection pressures, and...

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Source

Identifiers

PMID: 18351333
DOI: 10.1007/s00251-008-0279-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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