Article
ACE gene polymorphism and cardiac structure in patients with insulin resistance.
Molecular biology reports - 1 Apr 2009
Akin Fulya, Turgut Sebahat, Dursunoglu Dursun, Turgut Gunfer, Karasu Ugur, Gur Sukru
Abstract excerpt
AIMS: Angiotensin-converting enzyme (ACE) is a key enzyme in the production of angiotensin II, thus may participate in the modulation of cardiac growth. The aim of our study is to analyze the ACE gene I/D polymorphisms in patients with insulin resistance (IR) and to evaluate its relationship to left ventricular mass and functions. METHODS: Eighteen subjects (13 female and 5 male, mean age 39.8 +/- 14) with IR...
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