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Article

Inhibition of ADP-induced platelet aggregation by clopidogrel is related to CYP2C19 genetic polymorphisms.

Clinical and experimental pharmacology & physiology - 1 Aug 2008

Chen Bi-Lian, Zhang Wei, Li Qing, Li Ya-Lin, He Yi-Jing, Fan Lan, Wang Lian-Sheng, Liu Zhao-Qian, Zhou Hong-Hao

Abstract excerpt

1. Clopidogrel is one of the most important antithrombotic drugs but has different efficacies in different populations. The aim of the present study was to evaluate the contribution of CYP2C19 genetic polymorphisms to the inhibition of ADP-induced platelet aggregation by clopidogrel in healthy Ch...

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Share to Adenosine Diphosphate
Share to Aryl Hydrocarbon Hydroxylases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2C19

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Share to Polymorphism, Genetic

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Source

Identifiers

PMID: 18346178
DOI: 10.1111/j.1440-1681.2008.04915.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18346178-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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