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Article

Inhibition of ADP-induced platelet aggregation by clopidogrel is related to CYP2C19 genetic polymorphisms.

Clinical and experimental pharmacology & physiology - 1 Aug 2008

Chen Bi-Lian, Zhang Wei, Li Qing, Li Ya-Lin, He Yi-Jing, Fan Lan, Wang Lian-Sheng, Liu Zhao-Qian, Zhou Hong-Hao

Abstract excerpt

1. Clopidogrel is one of the most important antithrombotic drugs but has different efficacies in different populations. The aim of the present study was to evaluate the contribution of CYP2C19 genetic polymorphisms to the inhibition of ADP-induced platelet aggregation by clopidogrel in healthy Chinese volunteers. 2. Eighteen healthy male volunteers (six CYP2C19*1/CYP2C19*1, six CYP2C19*1/CYP2C19*2and*3 and six...

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Identifiers

PMID: 18346178
DOI: 10.1111/j.1440-1681.2008.04915.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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