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Article

Fibulin‐5 accelerates elastic fibre assembly in human skin fibroblasts

13 Mar 2008

Abstract excerpt

Fibulin-5 null mice display abnormalities in the elastic fibres in the dermis. We postulated, therefore, that fibulin-5 might be a regulator of elastic fibre assembly and stability. To clarify the role of fibulin-5 in elastic fibre formation, we employed in vitro systems that allowed increasing expression of elastic fibre components by gene transduction using retroviral vector constructs. First, the human...

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PMID: 18341572
DOI: 10.1111/j.1600-0625.2008.00709.x

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