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Article

Elastin gene polymorphisms in neovascular age-related macular degeneration and polypoidal choroidal vasculopathy.

Investigative ophthalmology & visual science - 1 Mar 2008

Kondo Naoshi, Honda Shigeru, Ishibashi Kazuki, Tsukahara Yasutomo, Negi Akira

Abstract excerpt

PURPOSE: To study and reveal genetic variation in the elastin gene (ELN) that may be associated with neovascular age-related macular degeneration (AMD) and/or polypoidal choroidal vasculopathy (PCV). Eyes with neovascular AMD and PCV exhibit substantially different structural alterations of the elastic layer in the Bruch's membrane. The hypothesis for the present study was that ELN polymorphisms may play a role...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 18326737
DOI: 10.1167/iovs.07-1145

Genes

ELN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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