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Article

Evidence of a novel gene HERPUD1 in polypoidal choroidal vasculopathy.

International journal of clinical and experimental pathology - 1 Jan 2015

Jin Enzhong, Bai Yujing, Huang Lvzhen, Zhao Min, Zhang Chunfang, Zhao Mingwei, Li Xiaoxin

Abstract excerpt

Polypoidal choroidal vasculopathy (PCV) is an exudative maculopathy, with clinical features distinct from neovascular age-related macular degeneration (nAMD) which is the leading cause of irreversible blindness in the elderly. Our studies focused on the genetic background and function of a novel gene HERPUD1 in PCV. HERPUD1 has been reported to increase the level of amyloid β (Aβ), which is a component of drusen...

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Share to Amyloid beta-Peptides
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26823705
PMCID: PMC4713491

Genes

HERPUD1
RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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