Article
[Abnormality of telomere maintenance linked to bone marrow failures].
Nihon rinsho. Japanese journal of clinical medicine - 1 Mar 2008
Yamaguchi Hiroki
Abstract excerpt
Telomeres are structural elements that seal and protect the ends of linear chromosomes from illegitimate recombination, end-to-end fusion, or being recognized as damaged DNA. These repeats are gradually lost with cellular replication and aging. Telomere attrition eventually leads to critically sh...
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