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[Both somatic and germline genetics of the TP53-pathway influence ovarian cancer incidence and survival].

Verhandlungen der Deutschen Gesellschaft fur Pathologie - 1 Jan 2007

Böhnke A, Jung J, Taubert H, Hauptmann S, Bartel F

Abstract excerpt

PURPOSE: Although TP53 is one of the most studied genes/proteins in ovarian carcinomas, the predictive value of TP53 alterations is still ambiguous. EXPERIMENTAL DESIGN: We performed analyses of the TP53 mutational status and its protein expression by immunohistochemistry. Moreover, the single nucleotide polymorphism SNP309 in the P2-promotor of the HDM2 gene was investigated. We correlated the results with the...

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PMID: 18314620

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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