Mutations of the lutropin/choriogonadotropin receptor that do not activate the phosphoinositide cascade allow hCG to induce aromatase expression in immature rat granulosa cells.

Abstract excerpt

Using primary cultures of immature rat granulosa cells and adenoviral infections we expressed two mutants of the human lutropin receptor (hLHR) that do not activate the phosphoinositide cascade. One mutant (hLFF) has the extracellular domain of the hLHR and the transmembrane and intracellular dom...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Aromatase
• Share to Chorionic Gonadotropin
• Share to Epidermal Growth Factor