Article
Characterization of knockdown resistance in DDT- and pyrethroid-resistant Culex quinquefasciatus populations from Sri Lanka.
Tropical medicine & international health : TM & IH - 1 Apr 2008
Wondji Charles S, Priyanka De Silva W A P, Hemingway Janet, Ranson Hilary, Parakrama Karunaratne S H P
Abstract excerpt
DDT and pyrethroid resistance in Culex quinquefasciatus have been previously reported in Sri Lanka, but the mechanisms involved have yet to be characterized. We report the presence of two mutant alleles of the sodium channel gene, the target site for both DDT and pyrethroid insecticides. Both mutations resulted in classic knockdown resistance (kdr) L1014F mutation because of either an A-to-T substitution or an...
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