Article
Novel real-time PCR assay detects widespread distribution of knock down resistance (kdr) mutations associated with pyrethroid resistance in the mosquito, Culex quinquefasciatus, in Thailand.
Pesticide biochemistry and physiology - 1 Aug 2022
Chamnanya Saowanee, Yanola Jintana, Nachaiwieng Woottichai, Lumjuan Nongkran, Walton Catherine, Somboon Pradya
Abstract excerpt
Susceptibility to pyrethroids in the mosquito Culex quinquefasciatus, the major vector of lymphatic filariasis, is being seriously threatened worldwide. Knockdown resistance (kdr), caused by mutations in the voltage gated sodium channel (VGSC) gene, particularly the L1014F mutation, is an important resistance mechanism. Our aim was to develop a real-time PCR with melt curve analysis to evaluate the distribution...
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