Article
DNA fingerprinting: the utilization of minisatellite probes to detect a somatic mutation in the proteus syndrome.
EXS - 1 Jan 1991
Schwartz C E, Brown A M, Der Kaloustian V M, McGill J J, Saul R A
Abstract excerpt
Syndromes with localized or segmental abnormalities have been proposed to be the result of a somatic mutation leading to the presence of somatic mosaicism in the tissue. The Proteus syndrome, with its hemihypertrophy, macrodactyly and exostoses, has features which would indicate that the phenotyp...
Topics
- Abnormalities, Multiple
- Child, Preschool
- DNA Fingerprinting
- DNA Probes
- DNA, Satellite
- Diseases in Twins
- Foot Deformities, Congenital
- Hamartoma
- Hand Deformities, Congenital
- Head
- Humans
- Male
- Mutation
- Syndrome