Ultrasonic approach to enhance signal-to-noise in three dimensional microarray.

Abstract excerpt

Three-dimensional polyacrylamide gel microarray (3-D gel microarray) has a strong adsorption for hybridzation probes with fluorescent label, resulting in high fluorescent background noise. The background noise has hampered the broad application of the microarray in scientific research. A low-frequency ultrasound of 40 kHz has been successfully employed to efficiently remove the nonspecifically bound fluorescent...

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