Article
Automated, computerized, feature-based phenotype analysis of slit lamp images of the mouse lens.
Experimental eye research - 1 Apr 2008
Yuen Jenny, Li Yi, Shapiro Linda G, Clark John I, Arnett Ernest, Sage E Helene, Brinkley James F
Abstract excerpt
Longitudinal studies of a variety of transgenic mouse models for lens development can create substantial challenges in database management and analysis. We report a novel, automated, feature-based informatics approach to screening lens phenotypes in a large database of slit lamp images. Digital slit lamp images of normal and abnormal lenses in eyes of wild type (wt), SC1 null and SPARC null transgenic mice were...
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