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The Neurospora crassa cyt-20 gene encodes cytosolic and mitochondrial valyl-tRNA synthetases and may have a second function in addition to protein synthesis.

Molecular and cellular biology - 1 Aug 1991

Kubelik A R, Turcq B, Lambowitz A M

Abstract excerpt

The cyt-20-1 mutant of Neurospora crassa is a temperature-sensitive, cytochrome b- and aa3-deficient strain that is severely deficient in both mitochondrial and cytosolic protein synthesis (R.A. Collins, H. Bertrand, R.J. LaPolla, and A.M. Lambowitz, Mol. Gen. Genet. 177:73-84, 1979). We cloned the cyt-20+ gene by complementation of the cyt-20-1 mutation and found that it contains a 1,093-amino-acid open reading...

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Identifiers

PMID: 1830127
DOI: 10.1128/mcb.11.8.4022-4035.1991
PMCID: PMC361206

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