Article
The Neurospora crassa colonial temperature-sensitive 3 (cot-3) gene encodes protein elongation factor 2.
Molecular & general genetics : MGG - 1 Feb 2001
Propheta O, Vierula J, Toporowski P, Gorovits R, Yarden O
Abstract excerpt
At elevated temperatures, the Neurospora crassa mutant colonial, temperature-sensitive 3 (cot-3) forms compact, highly branched colonies. Growth of the cot-3 strain under these conditions also results in the loss of the lower molecular weight (LMW) isoform of the Ser/Thr protein kinase encoded by the unlinked cot-1 gene, whose function is also involved in hyphal elongation. The unique cot-3 gene has been cloned...
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