Article
Phase 2 trial of docetaxel and gefitinib in the first-line treatment of patients with advanced nonsmall-cell lung cancer (NSCLC) who are 70 years of age or older.
Cancer - 1 May 2008
Simon George R, Extermann Martine, Chiappori Alberto, Williams Charles C, Begum Mubeena, Kapoor Rachna, Haura Eric B, Ismail-Khan Roohi, Schell Michael J, Antonia Scott J, Bepler Gerold
Abstract excerpt
BACKGROUND: This is a phase 2 study of chemotherapy-naive patients, 70 years of age or older, with nonsmall-cell lung cancer (NSCLC) who were treated with docetaxel and gefitinib. The primary endpoint was response rate (RR). Secondary endpoints were overall survival (OS) and progression-free survival (PFS). METHODS: Eligible patients were treated with docetaxel 75 mg/m(2) every 3 weeks and gefitinib 250 mg...
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