Randomized phase III trial of erlotinib versus docetaxel as second- or third-line therapy in patients with advanced non-small-cell lung cancer: Docetaxel and Erlotinib Lung Cancer Trial (DELTA).

doi:10.1200/JCO.2013.52.4694

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Randomized phase III trial of erlotinib versus docetaxel as second- or third-line therapy in patients with advanced non-small-cell lung cancer: Docetaxel and Erlotinib Lung Cancer Trial (DELTA).

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Jun 2014

Kawaguchi Tomoya, Ando Masahiko, Asami Kazuhiro, Okano Yoshio, Fukuda Masaaki, Nakagawa Hideyuki, Ibata Hidenori, Kozuki Toshiyuki, Endo Takeo, Tamura Atsuhisa, Kamimura Mitsuhiro, Sakamoto Kazuhiro, Yoshimi Michihiro, Soejima Yoshifumi, Tomizawa Yoshio, Isa Shun-ichi, Takada Minoru, Saka Hideo, Kubo Akihito

Abstract excerpt

PURPOSE: To investigate the efficacy of erlotinib versus docetaxel in previously treated patients with advanced non-small-cell lung cancer (NSCLC) in an epidermal growth factor receptor (EGFR) -unselected patient population. PATIENTS AND METHODS: The primary end point was progression-free survival (PFS). Secondary end points included overall survival (OS), response rate, safety, and analyses on EGFR wild-type...

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PMID: 24841974
DOI: 10.1200/JCO.2013.52.4694

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EGFR

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