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Article

Heteroplasmies detected in an amplified mitochondrial DNA control region from a small amount of template.

Journal of forensic sciences - 1 Mar 2008

Nakahara Hiroaki, Sekiguchi Kazumasa, Imaizumi Kazuhiko, Mizuno Natsuko, Kasai Kentaro

Abstract excerpt

When mitochondrial DNA (mtDNA) heteroplasmies are detected, they often confound forensic identification, especially if they are the result of poor biological sampling. In this study, we determined the ratio of heteroplasmy in samples that were amplified from a very small amount of template mtDNA or a few cells using a highly sensitive nested polymerase chain reaction (PCR) procedure and a direct sequencing...

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Identifiers

PMID: 18298490
DOI: 10.1111/j.1556-4029.2007.00655.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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