Article
Ancient DNA identification of early 20th century simian T-cell leukemia virus type 1.
Molecular biology and evolution - 1 Jun 2008
Calvignac Sébastien, Terme Jean-Michel, Hensley Shannon M, Jalinot Pierre, Greenwood Alex D, Hänni Catherine
Abstract excerpt
The molecular identification of proviruses from ancient tissues (and particularly from bones) remains a contentious issue. It can be expected that the copy number of proviruses will be low, which magnifies the risk of contamination with retroviruses from exogenous sources. To assess the feasibility of paleoretrovirological studies, we attempted to identify proviruses from early 20th century bones of museum...
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