Abnormal elongation of midpiece, absence of axoneme and outer dense fibers at principal piece level, supernumerary microtubules: a sperm defect of possible genetic origin?

Abstract excerpt

OBJECTIVE: To characterize a flagellar defect involving 95% of the sperm population from an infertile man. DESIGN: Case report. SETTING: Interdepartmental Centre for Research and Therapy of Male Infertility, Siena, Italy. PATIENT(S): A 42-year-old infertile man with severe asthenozoospermia. INTERVENTION(S): Family history, physical examination, hormonal analysis, microbial assays, semen analysis, transmission...

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• Asthenozoospermia
• Axoneme
• Genetic Predisposition to Disease
• Microtubules
• Spermatozoa