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The cys-loop ligand-gated ion channel gene superfamily of the nematode, Caenorhabditis elegans

20 Feb 2008

Abstract excerpt

The nematode, Caenorhabditis elegans, possesses the most extensive known superfamily of cys-loop ligand-gated ion channels (cys-loop LGICs) consisting of 102 subunit-encoding genes. Less than half of these genes have been functionally characterised which include cation-permeable channels gated by acetylcholine (ACh) and gamma-aminobutyric acid (GABA) as well as anion-selective channels gated by ACh, GABA,...

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PMID: 18288508
DOI: 10.1007/s10158-008-0068-4

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