Article
Structural genomic variation in ischemic stroke.
Neurogenetics - 1 May 2008
Matarin Mar, Simon-Sanchez Javier, Fung Hon-Chung, Scholz Sonja, Gibbs J Raphael, Hernandez Dena G, Crews Cynthia, Britton Angela, De Vrieze Fabienne Wavrant, Brott Thomas G, Brown Robert D, Worrall Bradford B, Silliman Scott, Case L Douglas, Hardy John A, Rich Stephen S, Meschia James F, Singleton Andrew B
Abstract excerpt
Technological advances in molecular genetics allow rapid and sensitive identification of genomic copy number variants (CNVs). This, in turn, has sparked interest in the function such variation may play in disease. While a role for copy number mutations as a cause of Mendelian disorders is well established, it is unclear whether CNVs may affect risk for common complex disorders. We sought to investigate whether...
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