Article
Premature ovarian failure and androgen receptor gene CAG repeat lengths weighted by X chromosome inactivation patterns.
Fertility and sterility - 1 Feb 2009
Sugawa Fumihiro, Wada Yuka, Maruyama Tetsuo, Uchida Hiroshi, Ishizuka Bunpei, Ogata Tsutomu
Abstract excerpt
The CAG repeat lengths weighted by X-inactivation ratios were significantly shorter in 58 Japanese patients with premature ovarian failure (POF) than in 42 age-matched control females with normal menses. The results suggest that short CAG repeats with a relatively high androgen receptor function may constitute a susceptibility factor for the development of POF.
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