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Article

IgM myeloma: a rare entity characterized by a CD20-CD56-CD117- immunophenotype and the t(11;14).

British journal of haematology - 1 Mar 2008

Feyler Sylvia, O'Connor Sheila J M, Rawstron Andy C, Subash Chezhian, Ross Fiona M, Pratt Guy, Drayson Mark T, Ashcroft John, Cook Gordon, Owen Roger G

Abstract excerpt

IgM myeloma is a very rare and poorly defined entity. In a detailed assessment of 10 cases, it was demonstrated that 70% had an aberrant phenotype based on the expression of CD19, CD45, CD27 and Cyclin D1 but all cases lacked CD56 and CD117. Interphase fluorescence in situ hybridization demonstrated deletion 13 in 50% while 5/8 cases assessed had a t(11;14). Despite the high incidence of the t(11;14), CD20 was...

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Share to Antigens, CD20
Share to CD56 Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 11

Share to Chromosomes, Human, Pair 14

Share to Immunoglobulin M

Share to Multiple Myeloma

Share to Proto-Oncogene Proteins c-kit

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Source

Identifiers

PMID: 18275432
DOI: 10.1111/j.1365-2141.2007.06969.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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