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Familial aggregation of left main coronary artery disease and future risk of coronary events in asymptomatic siblings of affected patients

7 Feb 2008

Abstract excerpt

We read with interest Fischer et al.'s1 recent paper on the heritability of angiographically diagnosed left main disease (LMD). They concluded that the presence of LMD in an index patient confers a three-fold increased risk of LMD in a sibling, confirming earlier findings of familial aggregation of location-specific coronary lesions.2 They further concluded that LMD, in a patient with myocardial infarction (MI),...

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PMID: 18263869
DOI: 10.1093/eurheartj/ehn035

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