Article
Utilization of F1 information in estimating QTL effects in F2 crosses between outbred lines.
Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie - 1 Feb 2008
Daley J W, Shepherd R K
Abstract excerpt
Quantitative trait loci (QTL) analysis in designed experiments is investigated using a mixed model framework through the modification of segment mapping techniques. Allele effects are modelled in the F1 generation allowing the estimation of additive substitution effects while accounting for QTL segregation within lines and differences in mean QTL effects between lines. The resulting approach is called F1 segment...
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