Article
5' ins/del and 3' VNTR polymorphisms in the apolipoprotein B gene in relation to lipids and coronary artery disease.
Clinical chemistry and laboratory medicine - 1 Jan 2008
Rebhi Lamia, Omezzine Asma, Kchok Kaouther, Belkahla Radhia, Ben Hadjmbarek Ibtihel, Rejeb Jihen, Ben Rejeb Nabila, Nabli Naoufel, Bibi Amina, Massoud Taieb, Abdelaziz Ahmed, Boughzala Essia, Bouslama Ali
Abstract excerpt
BACKGROUND: Studies that considered apolipoprotein B (APOB) gene polymorphisms as risk factors for coronary artery disease (CAD) have reported conflicting results. We sought to analyze the association between 5' ins/del and 3' VNTR polymorphisms of APOB, lipid parameters and CAD risk. METHODS: We recruited 251 patients with CAD, documented by coronary angiography, and 94 controls. Genotyping was performed by PCR....
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