Article
Symbiotic gut microbes modulate human metabolic phenotypes.
Proceedings of the National Academy of Sciences of the United States of America - 12 Feb 2008
Li Min, Wang Baohong, Zhang Menghui, Rantalainen Mattias, Wang Shengyue, Zhou Haokui, Zhang Yan, Shen Jian, Pang Xiaoyan, Zhang Meiling, Wei Hua, Chen Yu, Lu Haifeng, Zuo Jian, Su Mingming, Qiu Yunping, Jia Wei, Xiao Chaoni, Smith Leon M, Yang Shengli, Holmes Elaine, Tang Huiru, Zhao Guoping, Nicholson Jeremy K, Li Lanjuan, Zhao Liping
Abstract excerpt
Humans have evolved intimate symbiotic relationships with a consortium of gut microbes (microbiome) and individual variations in the microbiome influence host health, may be implicated in disease etiology, and affect drug metabolism, toxicity, and efficacy. However, the molecular basis of these microbe-host interactions and the roles of individual bacterial species are obscure. We now demonstrate a"transgenomic"...
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