The impact of JAK2 and MPL mutations on diagnosis and prognosis of splanchnic vein thrombosis: a report on 241 cases.

doi:10.1182/blood-2007-11-125328

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Article

The impact of JAK2 and MPL mutations on diagnosis and prognosis of splanchnic vein thrombosis: a report on 241 cases.

Blood - 15 May 2008

Kiladjian Jean-Jacques, Cervantes Francisco, Leebeek Franck W G, Marzac Christophe, Cassinat Bruno, Chevret Sylvie, Cazals-Hatem Dominique, Plessier Aurélie, Garcia-Pagan Juan-Carlos, Darwish Murad Sarwa, Raffa Sebastian, Janssen Harry L A, Gardin Claude, Cereja Sophie, Tonetti Carole, Giraudier Stéphane, Condat Bertrand, Casadevall Nicole, Fenaux Pierre, Valla Dominique C

Abstract excerpt

Myeloproliferative diseases (MPDs) represent the commonest cause of splanchnic vein thrombosis (SVT), including Budd-Chiari syndrome (BCS) and portal vein thrombosis (PVT), but their diagnosis is hampered by changes secondary to portal hypertension, while their influence in the outcome of SVT remains unclear. We assessed the diagnostic and prognostic value of JAK2 and MPL515 mutations in 241 SVT patients (104...

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Identifiers

PMID: 18250227
DOI: 10.1182/blood-2007-11-125328

Genes

JAK2
MPL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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