Article
Identification of a positively evolving putative binding region with increased variability in posttranslational motifs in zonadhesin MAM domain 2.
Molecular phylogenetics and evolution - 1 Oct 2005
Herlyn Holger, Zischler Hans
Abstract excerpt
Positive selection has been shown to be pervasive in sex-related proteins of many metazoan taxa. However, we are only beginning to understand molecular evolutionary processes on the lineage to humans. To elucidate the evolution of proteins involved in human reproduction, we studied the sequence evolution of MAM domains of the sperm-ligand zonadhesin in respect to single amino acid sites, solvent accessibility,...
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