Article
[Association between CYP1A1 gene polymorphism and intrahepatic cholestasis of pregnancy].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Feb 2008
Wang Xiaoli, Zhang Li, Ou Rong-qing, Wang Jing, Liu Shu-yun, Chen Qiang, Su Pin-can
Abstract excerpt
OBJECTIVE: To study the relationship between CYP1A1 genetic polymorphism and intrahepatic cholestasis of pregnancy (ICP) in Chengdu of China. METHODS: MspI and Ile/Val genotypes of CYP1A1 gene were detected with polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and allele-specific amplification-PCR (ASA-PCR) in a case-control study, including 100 cases of ICP and 100 controls. RESULTS:...
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