Beta-thalassemia intermedia and IVS-1 NT6 homozygosis in Brazil.

Article

Beta-thalassemia intermedia and IVS-1 NT6 homozygosis in Brazil.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Jan 1991

Costa F F, Tavella M H, Zago M A

Abstract excerpt

1. The molecular abnormality of a patient with thalassemia intermedia was identified by DNA amplification (PCR) combined with the use of synthetic oligonucleotide probes. 2. The patient is a homozygote for the T----C substitution at position 6 of the first intervening sequence (IVS1-6) of the bet...

Topics

Adult
Base Sequence
Brazil
Homozygote
Humans
Molecular Sequence Data
Mutation
Oligonucleotide Probes
Polymerase Chain Reaction
Thalassemia

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