Article
Influence of DNA damage and repair upon the risk of treatment related leukemia.
Leukemia & lymphoma - 1 Feb 2008
Guillem Vicent, Tormo Mar
Abstract excerpt
Therapy-related myelodysplasia and acute myeloid leukemia (t-MDS/AML) are malignancies occurring after exposure to chemotherapy and/or radiotherapy. Several studies have addressed cumulative dose, dose intensity and exposure to specific agents of preceding cytotoxic therapy in relation to the risk of developing such leukemia. Since only a small percentage of patients exposed to cytotoxic therapy develop...
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