Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Blockade of TNF receptor 1 reduces disease severity but increases parasite transmission during Plasmodium chabaudi chabaudi infection.

International journal for parasitology - 1 Jul 2008

Long Gráinne H, Chan Brian H K, Allen Judith E, Read Andrew F, Graham Andrea L

Abstract excerpt

Reducing host carriage of transmission-stage malaria parasites (gametocytes) is expected to decrease the population-wide burden of malaria. Some malaria disease severity is attributed to the induction of the pro-inflammatory cytokines TNF-alpha and lymphotoxin-alpha (LT-alpha), and we are interested in whether anti-malaria interventions which ameliorate the symptoms induced by those cytokines may have the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endemic Diseases
Share to Host-Parasite Interactions

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Malaria

Share to Mice, Inbred C57BL

Share to Plasmodium chabaudi

Share to Protein Precursors

Share to Receptors, Tumor Necrosis Factor, Type I

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 18226816
DOI: 10.1016/j.ijpara.2007.12.001

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Blockade of TNF receptor 1 reduces disease severity but increases parasite transmission during Plasmodium chabaudi chabaudi infection.PMID 18226816Read ↗

Parasite genetic diversity does not influence TNF-mediated effects on the virulence of primary rodent malaria infections.Semantic proximity Read ↗

Experimental manipulation of immune-mediated disease and its fitness costs for rodent malaria parasites.Semantic proximity Read ↗

Virulence, drug sensitivity and transmission success in the rodent malaria, Plasmodium chabaudi.Semantic proximity Read ↗

Mosquito transmission of the rodent malaria parasite Plasmodium chabaudiSemantic proximity Read ↗

ICAM-1 is a key receptor mediating cytoadherence and pathology in the Plasmodium chabaudi malaria modelSemantic proximity Read ↗

The effect of parasite dose on disease severity in the rodent malaria Plasmodium chabaudiSemantic proximity Read ↗

Rodent malaria models: insights into human disease and parasite biologySemantic proximity Read ↗

Disease severity in coinfected hosts: the importance of infection orderSemantic proximity Read ↗

Host-parasite interactions for virulence and resistance in a malaria model system.Semantic proximity Read ↗

The effects of host immunity on virulence-transmissibility relationships in the rodent malaria parasite Plasmodium chabaudi.Semantic proximity Read ↗

Enhancing malaria elimination in high-transmission settings: the synergy of concurrent vector control and chemotherapySemantic proximity Read ↗

MOSQUITO MORTALITY AND THE EVOLUTION OF MALARIA VIRULENCESemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.