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Article

Molecular and trophic mechanisms of tumorigenesis.

Endocrinology and metabolism clinics of North America - 1 Mar 2008

Levy Andy

Abstract excerpt

A significant proportion of pituitary macroadenomas, and by definition all microadenomas, regain trophic stability after an initial period of deregulated growth. Classical proto-oncogene activation and tumor suppressor mutation are rarely responsible, and no histologic or molecular markers reliably predict behavior. GNAS1 activation and the mutations associated with multiple endocrine neoplasia type 1 and Carney...

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Source

Identifiers

PMID: 18226729
DOI: 10.1016/j.ecl.2007.10.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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