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Article

Second hits in the FLCN gene in a hereditary renal cancer syndrome in dogs.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Feb 2008

Bønsdorff Tina B, Jansen Johan Høgset, Lingaas Frode

Abstract excerpt

In this study, samples from multifocal renal tumors from two dogs affected with renal cystadenocarcinoma and nodular dermatofibrosis (RCND) were collected for detection of putative second hits in the FLCN gene. Genomic DNA from the samples was typed at the previously identified disease-associated missense mutation and cDNA representing the entire coding region of the FLCN gene was sequenced for mutation...

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Source

Identifiers

PMID: 18219524
DOI: 10.1007/s00335-007-9088-3

Genes

FLCN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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