Article
[Genetic risk factor of Alzheimer's disease].
Rinsho shinkeigaku = Clinical neurology - 1 Nov 2007
Kuwano Ryozo
Abstract excerpt
The Japanese Genetic Study Consortium for Alzheimer's disease (JGSCAD) was organized in 2000 to discover strategies to delay onset and progression of dementia. To identify an additional gene (s) causing susceptibility to APOE-epsilon4 negative late-onset AD (LOAD), we performed single nucleotide polymorphisms (SNP)-based association analysis on chromosomes 10 with only the APOE-epsilon3*3 genotype. The...
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