Article
Evidence for association of chromosome 10 open reading frame (C10orf27) gene polymorphisms and multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Apr 2008
Goertsches Robert, Baranzini Sergio E, Morcillo Carlos, Nos Carlos, Camiña Montse, Oksenberg Jorge R, Montalban Xavier, Comabella Manuel
Abstract excerpt
A recent association study has provided evidence that chromosome 10q22.1 may contain candidate genes for multiple sclerosis (MS). We analysed two intronic and a non-synonymous single nucleotide polymorphism (SNP) of the C10orf27 gene in 571 patients with MS (relapsing remitting and primary progressive) and healthy controls. Adjusted comparisons revealed significant association with disease susceptibility for one...
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