Article
Vitiligo pathogenesis: autoimmune disease, genetic defect, excessive reactive oxygen species, calcium imbalance, or what else?
Experimental dermatology - 1 Feb 2008
Schallreuter K U, Bahadoran P, Picardo M, Slominski A, Elassiuty Y E, Kemp E H, Giachino C, Liu J B, Luiten R M, Lambe T, Le Poole I C, Dammak I, Onay H, Zmijewski M A, Dell'Anna M L, Zeegers M P, Cornall R J, Paus R, Ortonne J P, Westerhof W
Abstract excerpt
The pathobiology of vitiligo has been hotly disputed for as long as one remembers, and has been a magnet for endless speculation. Evidently, the different schools of thought--ranging, e.g. from the concept that vitiligo essentially is a free-radical disorder to that of vitiligo being a primary autoimmune disease--imply very different consequences for the best therapeutic strategies that one should adopt. As a...
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